Physics Colloquium - Friday, Sept. 29th, 2006, 4:00 P.M.

E300 Math/Science Center; Refreshments at 3:30 P.M. in Room E200

Dr. Timothy G. Buchman
Washington University in St. Louis

The times of our lives: Physiologic variability in critical illness and recovery

Healthy patients continue to be described as having "regular rates and rhythms". This characterization is now known to be incorrect: during the past quarter century, physiologists and chronobiologists have repeatedly associated variability in diverse processes (for example, heart rate, tidal volume and hormone secretion) with health. That variability declines with age and especially with critical illness. This lecture, which is aimed at a general audience, will explore the value of variability; the notion of synchronization; and the impact of current therapeutic strategies on recovery of lost variability and return to health.