Research Topics
(detailed descriptions coming soon...)
A) Cellular Biophysics
Protein trafficking into the nucleus (Imaging, FCS, and FRET studies)
Interaction of Nuclear Localization Signal cargoes and import receptor molecules, quantified in vivo
Forster Resonance Energy Transfer (FRET) imaging of protein-protein interactions in living cells
B) Photophysics
Excitation saturation
Photobleaching
Blinking and excited state reactions in fluorescent proteins
C) Development
New data analysis theories and procedures
Multispectral imaging and FCS
D) Diagnostics
High sensitivity detection of specific nucleic acid sequences using dual-color FCS