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Dr. Laura Finzi
400 Dowman Dr.
Math and Science Center
Room: N246
Phone: 404-200-1806
Email: lfinzi@emory.edu
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About the lab

Our research is focused on the elucidation of the molecular mechanisms of transcriptional regulation. We use single molecule techniques such as the tethered particle motion technique (TPM), magnetic tweezers (MT), atomic force microscopy (AFM) and single molecule fluorescence together with more traditional biochemical and biomolecular techniques. We develop instrumentation and computational analyses as needed to carry out our investigations. Our research interests span loop-based genetic switches, transcription roadblocks, the interplay between transcription and DNA supercoiling, topoisomerases and DNA mechanics.

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Jan 11, 2021 - Jin's review on "Basic mechanisms and kinetics of pause-interspersed transcript elongation" has been published in Nucleic Acids Research. Congratulations, Jin!

Dec 01, 2020 - Joe received Highest Honors from the Thesis committee, Congratulations Joe!

Nov 29, 2020 - Joe Piccolo will be defending his Honors Thesis this Tuesday, December 1, 2020, 4:00 pm EST. His thesis Title: "Electromagnetic Tweezer Development: Improving Single-Molecule Techniques for the Study of DNA Mechanics and Gene Transcription".

We are all cheering for you Joe!

Nov 09, 2020 - Welcome postdoctoral fellow Eugeniu Ostrofet!

Sep 1, 2020 - Welcome postdoctoral fellow Yue Lu! Yue comes from the lab of Prof. Piero Bianco at U. Buffalo where he was studying DNA replication.

Aug 27, 2020 - Congratulations to former lab undergraduates Yoojin and Chandler who are engaged to get married!!!!!

May 27, 2020 - Zixing (Betty) Zheng received Highest Honors! Her Honors Thesis is entitled, "Nanomechanics of Diaminopurine and inosine-substituted DNA".

Jan 16, 2020 - The Finzi-Dunlap lab and the C-Trap facility at Emory University seek a motivated experimentalist to study transcriptional regulation, and supervise the use of the new NSF/Emory-sponsored C-Trap instrument from Lumicks, which integrates optical tweezers, single-molecule fluorescence detection, and microfluidics. The position is a unique opportunity to do cutting edge research and collaborate with a variety of exceptional investigators. More detailed requirements can be found in "News Archives...".

News Archives...