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Dr. Laura Finzi
400 Dowman Dr.
Math and Science Center
Room: N246
Phone: 404-727-4930
Email: lfinzi@emory.edu
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About the lab

Our research is focused on the elucidation of the molecular mechanisms of transcriptional regulation. We use single molecule techniques such as the tethered particle motion technique (TPM), magnetic tweezers (MT), atomic force microscopy (AFM) and single molecule fluorescence together with more traditional biochemical and biomolecular techniques. We develop instrumentation and computational analyses as needed to carry out our investigations. Our research interests span loop-based genetic switches, transcription roadblocks, the interplay between transcription and DNA supercoiling, topoisomerases and DNA mechanics.

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News

February 17-21, 2018 - Laura was invited to speak at the Biophysical Society Meeting in San Francisco (2/17 - 2/21). The symposium "DNA Supercoiling" will be co-chaired by her and Sara Harris from the University of Leeds, UK. See BPS for more details.

July 16-22, 2017 - Yan Yan attended the 2017 CPLC Summer School at University of Illinois at Urbana-Champaign on July 16-22, 2017.

April 6-9, 2017 - Laura has organized the first annual Southeastern Single Molecule Biophysics Networking Meeting, to be held at Amicalola Falls Lodge in Georgia's Chattahoochee National Forrest. For more information see the meeting website: www.southeastsm.org.

Feb 13, 2017 - Yan Yan gave a platform talk at the annual Biophysical Society meeting in New Orleans, entitled "Protein-mediated Loopts in Supercoiled DNA Create Large Topological Domains". For more information check out the abstract (DOI:10.1016/j.bpj.2016.11.938).
Dan Kovari and Zsuzsanna Vörös also gave poster presentations at the meeting. You can find Dan's abstract here (DOI: 10.1016/j.bpj.2016.11.421), and Zsuzsanna's here (DOI: 10.1016/j.bpj.2016.11.1169).

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