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Dr. Laura Finzi
400 Dowman Dr.
Math and Science Center
Room: N246
Phone: 404-727-4930
Email: lfinzi@emory.edu
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2017 Publications

D.T. Kovari, Y. Yan, L. Finzi, D. Dunlap
"Tethered Particle Motion: AN Easy Technique for Probing DNA Topology and Interactions with Transcription Factors", Single Molecule Analysis, 2017. DOI: 10.1007/978-1-4939-7271-5_17

Z. Vörös, Y. Yan, D. Kovari, L. Finzi, D. Dunlap
"Proteins mediating DNA loops effectively block transcription", Protein Science, 2017. DOI: 10.1002/pro.3156

S. Ucuncuoglu, D.A. Schneider, E.R. Weeks, D. Dunlap, L. Finzi "Chapter Sixteen - Multiplexed, Tethered Particle Microscopy for Studies of DNA-Enzyme Dynamics", Methods in Enzymology, 2017. DOI: 10.1016/bs.mie.2016.08.008

2016 Publications

S. Ucuncuoglu, K. L. Engel, P. K. Purohit, D. D. Dunlap, D. A. Schneider, L. Finzi
“Direct characterization of transcription elongation by RNA polymerase I”, Plos One, 2016. DOI:10.1371/journal.pone.0159527. eCollection 2016

Laura Finzi and Wilma K. Olson
"The emerging role of DNA supercoiling as a dynamic player in genomic structure and function" Biophysics Reviews, 2016. DOI:10.1007/s12551-016-0214-x

Laura Finzi and David D. Dunlap
“Supercoiling biases the formation of loops involved in gene regulation”, Biophysics Reviews, 2016. DOI:10.1007/s12551-016-0211-0

Suleyman Ucuncuoglu, David A. Schneider, Eric Weeks, David Dunlap, and Laura Finzi
“Multiplexed, tethered particle microscopy for studies of DNA-enzyme dynamics”, Methods in Enzymology, accepted.

2015 Publications

M.Fernandez, Q. Shao, C.Fountain, L. Finzi, and D. Dunlap
"E. coli gyrase fails to negatively supercoil diaminopurine-substituted DNA" Journal of Molecular Biology, 2015. DOI:10.1016/j.jmb.2015.04.006

2014 Publications

Y.Ding, C. Manzo, G.Flucrand, F.leng, D. Dunlap, and L. Finzi
"DNA supercoiling: A regulatory signal for the Lambda repressor" PNAS, 2014. DOI: 10.1073/pnas.1320644111

D.Priest, S.Kumar, Y.Yan, D.Dunlap, I.Dodd, K.Shearwin
"Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E.coli cells" PNAS, 2014. DOI: 10.1073/pnas.1410764111

S.Kumar, C. Manzo, C.Zurla, S.Ucuncuoglu, L. Finzi, and D. Dunlap
"Enhanced tethered-particle motion analysis reveals viscous effects" Biophys J, 2014. DOI: 10.1016/j.bpj.2013.11.4501

2013 Publications

M.A. Mendes, R.F. Guerra, M.C. Berns, C. Manzo, S. Masiero, L. Finzi, M. M. Kater, and L. Colombo
"MADS Domain Transcription Factors Mediate Short-Range DNA Looping That Is Essential for Target Gene Expression in Arabidopsis" The Plant Cell, 2013. DOI:10.1105/tpc.112.108688

N. Gao, K.E. Shearwin, J. Mack, L. Finzi, and D. Dunlap
"Purification of Bacteriophage Lambda Repressor" Protein Expression and Purification, 2013. DOI:10.1016/j.pep.2013.06.013

H. Wang, I.B. Dodd, D.D. Dunlap, K.E. Shearwin, and L. Finzi
"Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor" NAR, 2013. DOI: 10.1093/nar/gkt298.

L. Finzi and D. Dunlap
"Tethered particle Microscopy (TPM)" in "Encyclopedia of Biophysics", Springer (Berlin Heidelberg), 2579-2582 (2013). Tethered particle Microscopy (TPM)

2012 Publications

C. Manzo, C. Zurla, D. Dunlap, and L. Finzi
"The effect of non-specific binding of lambda repressor on DNA looping dynamics" Biophys. J.,103(8),1753,2012. DOI: 10.1016/j.bpj.2012.09.006.

S. Goyal, C. Foutain, D. Dunlap, F. Family, and L. Finzi
"Stretching DNA to quantify nonspecific protein binding" Phys. Rev. E, 2012. DOI: 10.1103/PhysRevE.86.011905.

Q. Shao, S. Goyal, L. Finzi, and D. Dunlap
"Physiological Levels of Salt and Polyamines Favor Writhe and Limit Twist in DNA" Macromolecules, 2012. DOI: 10.1021/ma300211t.

2011 Publications

D. Lewis, P. Le, C. Zurla, L. Finzi, and S. Adhya
"Multilevel autoregulation of lambda repressor protein CI by DNA looping in vitro" PNAS, 2011. DOI: 10.1073/pnas.1111221108.

D. Dunlap, C. Zurla, C. Manzo and L. Finzi
"Probing DNA Topology Using Tethered Particle Motion" in "methods in Molecular Biology: Single-Molecule Analysis: Methods and Protocols"
eds. E.J.G. Peterman and G Wuite, series editor John Walker, Springer vol. 783, pp. 295-313, 2011. DOI 10.1007/978-1-61779-282-3_16.

2010 Publications

L. Finzi, C. Manzo, C. Zurla, H. Wang, D. Lewis, S. Adhya and D. Dunlap
"DNA Looping in Prophage Lambda: New Insight from Single-Molecule Microscopy" in "Biophysics of DNA-protein interactions: From single molecules to biological systems"
Eds. M. Williams and L. J Maher, Springer pp. 193-212, 2010. DOI 10.1007/978-0-387-92808-1.

Paul Liebesny, Sachin Goyal, David Dunlap, Fereydoon Family and Laura Finzi
"Determination of the Number of Protein Bound non-specifically to DNA" JPCM, DOI:10.1088/0953-8984/22/41/414104 (2010)

L. Finzi and D. Dunlap
"Single-molecule approaches to structure, kinetics and thermodynamics of transcriptional regulatory nucleoprotein complexes" minireview, JBC, DOI:10.1074/jbc.R109.062612 (2010)

C. Manzo and L. Finzi
"Quantitative analysis of DNA looping kinetics from tethered particle motion experiments" Methods in Enzymology, Ed. Nils G. Walter, 2010

D. E. A. Lewis, S. J. Lee, S. Semsey, K. Virnik, L. Finzi and S. Adhya
"Role of HU in regulation of gal promoters" in " Bacterial Chromatin"
Eds: C. Dorman and R. T. Dame, 2010 Springer DOI: 10.1007/978-90-481-3473-1_17

2009 Publications

H. Wang, L. Finzi, D. E. A. Lewis, D. D. Dunlap
"AFM Studies of Lambda Repressor Oligomers Securing DNA Loops" Current Pharmaceutical Biotechnology, 10, 494-501 (2009)

C. Zurla, C. Manzo, D. D. Dunlap, D. E. A. Lewis, S. Adhya, L. Finzi
"Direct demonstration and quantification of long-range DNA looping by the lambda bacteriophage repressor" NAR, DOI:10.1093/nar/gkp134 (2009)

L. Finzi
"Perspectives on DNA looping", in IMA Volume on "Mathematics of DNA structure, Function, and Interactions" Eds
C. J. Benham, S. Harvey, W. K. Olson, D. L. Sumners, and D. Swigon Spring Science-Business Media, LLC,DOI 10.1007/978-1-4419-0670-0

2008 Publications

G. Lia, M. Indrieri, T. Owen-Hughes, L. Finzi, A. Podesta', P. Milani, D.Dunlap
"ATP-dependent looping of DNA by ISWI", Special issue:" From single molecules and single cells to tissue imaging" Journal of Biophotonics 4,280-286 (2008)

G. Lia, S. Semsey, D. e. lewis, S. Adhya, D. Besinmon, D. Dunlap, L. Finzi
"The Antiparallel loops in Gal DNA" NAR, 36, 4204-4210 (2008)

2007 Publications

C. Zurla, G. Bertoni, F. Valle, G. Dietler, L. Finzi, D. Dunlap
"Architectural role of IHF in the regulation of transcription at the single molecule level" Biophysical Chemistry 128, 245 - 252 (2007)

F. Guerra, L. Imperadori, D. Dunlap, R. Mantovani, L. Finzi
"DNA Compaction by the nuclear factor-Y" Biophy. J., 93(1):176-182 (2007)

J. F. Beausang, C. Zurla, C. Manzo, D. Dunlap, L. Finzi, and P. Nelson
"DNA Looping Kinetics Analyzed Using Diffusive Hidden Markov Model" Biophys. J. - 92:L64-L66 (2007)

2006 Publications

J. F. Beausang, C. Zurla, L. Sullivan, L. Finzi, P. C. Nelson
"Elementary simulation of tethered Brownian motion" AJP q-bio.BM/0610007

P. Nelson, C. Zurla, D. Brogioli, J. F. Beausang, L. Finzi, and D. Dunlap
"Tethered Particle Motion as a Diagnostic of DNA Tether Length" The Journal of Physical Chemistry B, 110 (34): 17260-17267 (2006)

C. Zurla, A Franzini, G. Galli, D.D. Dunlap, D.E.A. Lewis, S. Adhya and L. Finzi
"Novel tethered particle motion analysis of CI protein-mediated DNA looping in the regulation of bacteriophage lambda" Journal of Physics:Condensed Matter, 18, S225-S234 (2006)

2005 Publications

A. Podesta M. Indrieri, D. Brogioli, J. S. Manning, P. Milani, R. Guerra, L. Finzi, D. Dunlap
"Positively charged surfaces increase the flexibility of DNA" Biophys J., 89:2558-2563 (2005)

E. Consoli, R. Croce, D. Brogioli, D. Dunlap and L. Finzi
"Diffusion of phosphorylated and non-phosphorylated Light Harvesting Complex II in the thylakoid membranes" EMBO reports, 6(8):782-6 (2005)

G. Garab, P. Galaida, I. Pomozi, L. Finzi, T. Praznovszky, P. Ormos, H. Van Amerongen
"Alignment of biological microparticles by polarized laser beam" Eur. Biophys. J., 34(4):335-43 (2005)

M. Kooiker, C. Airoldi, A. Losa, P.S. Manzotti, L. Finzi, M. M. Kater and L. Colombo
"Basic pentacysteine1 a GA-Binding Protein that Induces Conformational Changes in the Regulatory Region of the Homeotic Arabidopsis Gene SEEDSTICK" The Plant Cell, 17:722-729 (2005)

2004 Publications

A. Podesta L. Imperadori, W. Colnaghi, L. Finzi, P. Milani and D. D. Dunlap
"Atomic Force Microscopy studies of DNA deposited on poly-L-ornithine coated mica" Journal of Microscopy 215:236-240 (2004)

2003 Publications

G. Lia, D. Bensimon, V. Croquette, J-F. Allemand, D. Dunlap, DAE. Lewis, S. Adhya, L. Finzi
"Supercoiling and denaturation in GalR/HU-mediated DNA looping as seen by single-molecule microscopy" PNAS, 100:11373-377 (2003)

L. Finzi and D. Dunlap
"Single molecule studies of DNA architectural changes induced by regulatory proteins" in Methods in Enzymology, invited article, Eds. Adhya & Garges, vol 370:369-378 (2003)

2002 Publications

M. Capitanio, G. Romano, R. Ballerini, D. Dunlap, L. Finzi, M. Giuntini and F.S. Pavone
"Calibration of an Optical Tweezer with DIC Signals" Reviews of Scientific Instruments, 73:1687-1696 (2002)

2001 Publications

L. Finzi, P. Galajda, and G. Garab
"Labeling phosphorylated LHCII with microspheres for tracking studies and force measurements" J. Photochem. Photobiol B:Biology, 65:1-4 (2001)

L. Sacconi, G. Romano, R. Ballerini, M. Capitanio, M. De Pas, D. Dunlap, M. Giuntini, L. Finzi and F.S. Pavone
"A 3D micro-TOP magneto-optical trap for micro-objects manipulation" Optics Letters, 26:1359-61, (2001)

1995 Publications

L. Finzi and J. Gelles
"Measurement of Lac Repressor-mediated loop formation and Breakdown in Single DNA molecules" Science 267, 378-380 (1995)

1992 Publications

S. Smith, L. Finzi and C. Bustamante
"Direct Mechanical Measurements of the Elasticity of single DNA molecules Using Magnetic Beads" Science 258:1122 (1992)

Complete List of Published Work in MyBibliography: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40647244/?sort=date&direction=descending”