Professor Laura Finzi receives Major Research Instrumentation (MRI) grant from the National Science Foundation (NSF) for single molecule optical tweezers fluourescence microscope.
Professor Laura Finzi has received a Major Research Instrumentation (MRI) grant from the National Science Foundation (NSF) for the acquisition of an advanced microscope that combines optical tweezers for high precision mechanical pulling, and nanometer-resolution fluorescence detection for spectroscopic localization, of single molecules in microfluidic cells. The instrumentation will be used by a multi-investigator team headed by Professor Finzi that will address a broad array of questions, that span genome transcription and maintenance, mechano-biochemistry of muscle protein function, shear sensing in blood, the design of molecular tension sensors and motors, and materials nano-physics. The microscope will be part of the Core Research Facilities at Emory that are shared among the research Universities in the Atlanta area through the Georgia Research Alliance.
A video that describes the basic functional features and capabilities of the Lumicks C-Trap Optical Tweezers-Fluorescence Microscope instrument is available here.